Dmog Stressmarq

Lab Reagents

Human IgG antibody Laboratories manufactures the dmog stressmarq reagents distributed by Genprice. The Dmog Stressmarq reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact Stressmarq Biosciences Inc.. Other Dmog products are available in stock. Specificity: Dmog Category: Stressmarq

Serum / Plasma information

17-AAG (Hsp90 inhibitor)
SIH-100A	Stressmarq	1 mg	EUR 188
Glendanamycin (GA), a benzoquinone ansamycin antibiotic, interferes with the action of Hsp90 leading to degradation of Hsp90 client proteins. GA itself however has undesirable properties such as poor aqueous solubility and liver toxicity therefore, Show more
Description: The substance 17-AAG is a hsp90 inhibitor. It is synthetically produced and has a purity of >99%. The pure substance is red to dark red powder which is soluble in DMSO (>50 mg/ml) or ethanol (5 mg/ml).

Geldanamycin (Hsp90 inhibitor)
SIH-111A	Stressmarq	1 mg	EUR 137
Glendanamycin (GA), a benzoquinone ansamycin antibiotic, interferes with the action of Hsp90 leading to degradation of Hsp90 client proteins. GA itself however has undesirable properties such as poor aqueous solubility and liver toxicity therefore, Show more
Description: The substance Geldanamycin is a hsp90 inhibitor. It is produced by fermentation and has a purity of >95%. The pure substance is yellow solid which is slightly soluble in methanol, chloroform or DMSO (10 mg/ml); insoluble in water.

Geldanamycin (Hsp90 inhibitor)
SIH-111B	Stressmarq	5 mg	EUR 289
Geldanamycin is a benzoquinoid ansamycin produced by Streptomyces hygroscopicus. It binds specifically to heat shock protein HSP90 and downregulates target proteins including tyrosine kinases, steroid receptors, transcription factors and cell cycle r Show more
Description: The substance Geldanamycin is a hsp90 inhibitor. It is produced by fermentation and has a purity of >95%. The pure substance is yellow solid which is slightly soluble in methanol, chloroform or DMSO (10 mg/ml); insoluble in water.

Geldanamycin- Biotin (Hsp90 inhibitor)
SIH-112A	Stressmarq	1 mg	EUR 272
Geldanamycin is a benzoquinoid ansamycin produced by Streptomyces hygroscopicus. It binds specifically to heat shock protein HSP90 and downregulates target proteins including tyrosine kinases, steroid receptors, transcription factors and cell cycle r Show more
Description: The substance Geldanamycin- Biotin is a hsp90 inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is purple solid which is soluble in DMSO.

Geldanamycin- FITC (Hsp90 inhibitor)
SIH-113A	Stressmarq	1 mg	EUR 290
Geldanamycin is a benzoquinoid ansamycin produced by Streptomyces hygroscopicus. It binds specifically to heat shock protein HSP90 and downregulates target proteins including tyrosine kinases, steroid receptors, transcription factors and cell cycle r Show more
Description: The substance Geldanamycin- FITC is a hsp90 inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is purple solid which is soluble in DMSO.

17-DMAG (Hsp90 inhibitor)
SIH-114-5MG	Stressmarq	5 mg	EUR 468
17-DMAG is a water soluble & cell-permeable analog of Geldanamycin and 17-AAG (1). It binds to the APTase site of human Hsp90a with high affinity, has cytotoxic activity against many cancer cell lines (2), and acts as angiogenesis inhibitor (3). This Show more
Description: The substance 17-DMAG is a hsp90 inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is purple solid which is soluble in DMSO (30 mg/ml) and ethanol (10 mg/ml).

17-DMAG (Hsp90 inhibitor)
SIH-114A	Stressmarq	1 mg	EUR 188
17-DMAG is a water soluble & cell-permeable analog of Geldanamycin and 17-AAG (1). It binds to the APTase site of human Hsp90a with high affinity, has cytotoxic activity against many cancer cell lines (2), and acts as angiogenesis inhibitor (3). This Show more
Description: The substance 17-DMAG is a hsp90 inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is purple solid which is soluble in DMSO (30 mg/ml) and ethanol (10 mg/ml).

17-GMB-APA-GA (Hsp90 inhibitor)
SIH-115A	Stressmarq	1 mg	EUR 290
An analog of geldanamycin containing a maleimido moiety suitable for preparation of geldanamycin immunoconjugates (1-3). Looking for more information on HSP90? Visit our new HSP90 Scientific Resource Guide at http://www.HSP90.ca.
Description: The substance 17-GMB-APA-GA is a hsp90 inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is purple solid which is soluble in DMSO (>25 mg/ml) and ethanol (10 mg/ml).

Herbimycin A (Hsp90 inhibitor)
SIH-116A	Stressmarq	100 µg	EUR 231
Herbimycin A, a benzoquinoid ansamycin antibiotic, irreversibly and selectively inhibits tyrosine kinases by reacting with thiol groups (1,2). It is effective on Src, Yes, Fps, Ros, Abl and ErbB oncogene products (1-3) and inhibits thrombin-induced t Show more
Description: The substance Herbimycin A is a hsp90 inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble in DMSO (>25 mg/ml) and ethanol (10 mg/ml).

Herbimycin A (Hsp90 inhibitor)
SIH-116B	Stressmarq	1 mg	EUR 986
Herbimycin A, a benzoquinoid ansamycin antibiotic, irreversibly and selectively inhibits tyrosine kinases by reacting with thiol groups (1,2). It is effective on Src, Yes, Fps, Ros, Abl and ErbB oncogene products (1-3) and inhibits thrombin-induced t Show more
Description: The substance Herbimycin A is a hsp90 inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble in DMSO (>25 mg/ml) and ethanol (10 mg/ml).

Radicicol (Hsp90 inhibitor)
SIH-117A	Stressmarq	1 mg	EUR 202
Radicicol inhibits src (IC50=0.27µM) and src-like kinases(1), leading to hypophosphorylation of retinoblastoma tumor suppressor protein(2). It causes morphological reversion of ras-transformed cells(3) and leads to selective depletion of Raf kinase( Show more
Description: The substance Radicicol is a hsp90 inhibitor. It is produced by fermentation and has a purity of 0.97. The pure substance is white to yellow solid which is soluble in DMSO.

TKD Peptide (Hsp70 Peptide) (Hsp70 Peptide)
SIH-118A	Stressmarq	1 mg	EUR 312
Hsp70 genes encode abundant heat-inducible 70-kDa hsps (hsp70s). In most eukaryotes hsp70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplas Show more
Description: The substance TKD Peptide (Hsp70 Peptide) is a hsp70 peptide. It is synthetically produced and has a purity of >98%. The pure substance is solid which is In aqueous solution.

TKD Peptide (Hsp70 Peptide): FITC (Hsp70 Peptide)
SIH-119A	Stressmarq	1 mg	EUR 359
Hsp70 genes encode abundant heat-inducible 70-kDa hsps (hsp70s). In most eukaryotes hsp70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplas Show more
Description: The substance TKD Peptide (Hsp70 Peptide): FITC is a hsp70 peptide. It is synthetically produced and has a purity of >98%. The pure substance is solid which is In aqueous solution.

MAPKII Kinase Inhibitor (Hsp25 Kinase Inhibitor)
SIH-120A	Stressmarq	1 mg	EUR 179
The MAPK (mitogen activated protein kinase) comprises a family of ubiquitous praline-directed, protein serine/threonine kinases which signal transduction pathways that control intracellular events including acute responses to hormones and major devel Show more
Description: The substance MAPKII Kinase Inhibitor is a hsp25 kinase inhibitor. It is synthetically produced and has a purity of >95%. The pure substance is white solid which is soluble in DMSO or H20.

YM-01 (Hsp70 Inhibitor)
SIH-121-10MG	Stressmarq	10 mg	EUR 249
YM-01 is an allosteric Hsp70 inhibitor. It binds with in Hsp70's nucleotide binding domain, adjacent to ATP/ADP binding pocket. It inhibits J-stimulated ATP turnover rate. It blocks Hsc70-bag1 interaction both in vitro and in vivo and enhances bindin Show more
Description: The substance YM-01 is a hsp70 inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is orange red solid which is soluble in warm water (2 mg/ml) .

YM-01 (Hsp70 Inhibitor)
SIH-121-25MG	Stressmarq	25 mg	EUR 434
YM-01 is an allosteric Hsp70 inhibitor. It binds with in Hsp70's nucleotide binding domain, adjacent to ATP/ADP binding pocket. It inhibits J-stimulated ATP turnover rate. It blocks Hsc70-bag1 interaction both in vitro and in vivo and enhances bindin Show more
Description: The substance YM-01 is a hsp70 inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is orange red solid which is soluble in warm water (2 mg/ml) .

YM-08 (Hsp70 Inhibitor)
SIH-122-10MG	Stressmarq	10 mg	EUR 249
YM-08 is a Heat Shock Protein 70 (Hsp70) inhibitor that is blood-brain barrier permeable. YM-08 is a neutral derivative of the Hsp70 inhibitor MKT-077. MKT-077 reduces tau levels in cellular models, but it doesn?t penetrate the blood brain barrier. A Show more
Description: The substance YM-08 is a hsp70 inhibitor. It is synthetically produced and has a purity of >99%. The pure substance is yellow-orange solid which is soluble in DMSO.