Depressive and anxiety symptomatology among people with asthma or atopic dermatitis: a population-based investigation using the UK Biobank data
August 16, 2020

Depressive and anxiety symptomatology among people with asthma or atopic dermatitis: a population-based investigation using the UK Biobank data

By Alexis

This study investigated the relationship of depression and anxiety symptomatology (DAS) with asthma and atopic dermatitis (AD) diagnosis during mid-adulthood. This study used data from 502 641 participants in the UK Biobank. Neutrophil to Lymphocyte Ratio (NLRs) of patients with asthma and AD are calculated and evaluated in relation to the DAS, measured through the Patient Health Questionnaire-4 (PHQ-4).

The age of onset of asthma or AD association with the DAS is also expected. Multivariable regression analysis was conducted between participants with asthma or AD, compared with those without the disorder. Of the 58 833 participants with asthma and 13 462 with AD, the prevalence of DAS was 11.7% and 2.7%, respectively. DAS increased among participants with either asthma or AD, which is the highest in patients who have both (β = 0.41, 95% confidence interval (95% CI), 0.34,0.49).

NLR show a linear increase with PHQ scores in patients with asthma, (tertile 1, β = 0.30, 95% CI, 0.27,0.34; tertile 2, β = 0.36, 95% CI, 0.32,0.39, and tertile 3, β = 0.43, 95% CI 0.39,0.46). Inverted U-shaped association was seen between the age of onset of asthma and PHQ, with the 40-59 age group (β = 0.54, 95% CI 0.48,0.59) show the highest risk, followed by 60 + (β = 0.43, 95% CI, 0.34,0.51 and the 20-39 group (β = 0.32, 95% CI 0.27,0.38). the same pattern appears in the AD.

Asthma and AD is associated with an increase in the watershed during the mid-adulthood, becoming the strongest among participants good reporting relationship disorders. A dose-response relationship between NLR and DAS observed. Asthma or AD onset during the middle adult years (40-59) was associated with the highest increase in the watershed.


Objective: To investigate the clinical characteristics and prognostic factors of adult rhabdomyosarcoma (RMS) of the nasal cavity and sinuses.

Methods: 35 adult patients with RMS, including 22 with embryonal type and 13 with type of acinar. Surgery + chemoradiotherapy (17 cases), surgery + radiotherapy (6 cases), surgery + chemotherapy (7 cases) (4 cases of implantation of seeds after surgery and chemotherapy)

 Depressive and anxiety symptomatology among people with asthma or atopic dermatitis: a population-based investigation using the UK Biobank data
Depressive and anxiety symptomatology among people with asthma or atopic dermatitis: a population-based investigation using the UK Biobank data

[Effect of the stage timpanoplasti for stapes fixation with tympanosclerosis]

Objective: To evaluate the results and complications heard from one stage timpanoplasti in patients with stapes fixation for tympanosclerosis.

Methods: diagnosed with chronic otitis media. For all patients, the plaque tympanosclerotic around stapes was removed for the mobilization of the stapes. Then ossicular chain was reconstructed by autogenous incus or PORP. Pre-and post-operative results of audiometry (500 Hz, 1 kHz, 2 kHz and 4 kHz) were evaluated for each patient. The increase in pure-tone average of 10 dB postoperative accepted as a criterion of success.

Results: Complications included temporary facial paralysis (1/61), vertigo while (2/61), mild elevations in bone conduction threshold (2/61) and delayed healing of the tympanic membrane (1/61). Postoperatively (1 and 3 months) increased bone conduction thresholds at frequencies of 1 and 2 kHz (P <0.01). Postoperatively (1 and 2 years old) improved air conduction thresholds at all frequencies (P <0.01 or P <0.05). A ≥10 dB gain in pure-tone average was found in 44 (72.13%) patients at 1 year after surgery. Air conduction level increased significantly in both autogenous incus and PORP group (P <0.01). There was no difference on the survival rates between the two groups (P> 0.05).

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HIV Seroconversion Panel Donor# 67512 (22 X 1 mL)

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HIV Seroconversion Panel Donor# 64578 (8 X 1 mL)

HIV9022 8 X 1 mL
EUR 1548.64
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 64578 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 67706 (22 X 1 mL)

HIV9023 22 X 1 mL
EUR 1548.64
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 67706 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 64469 (12 X 1 mL)

HIV9024 12 X 1 mL
EUR 1548.64
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 64469 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 67996 (12 X 1 mL)

HIV9025 12 X 1 mL
EUR 1548.64
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 67996 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 68205 (7 X 1 mL)

HIV9026 7 X 1 mL
EUR 1548.64
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 68205 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 67860 (7 X 1 mL)

HIV9028 7 X 1 mL
EUR 1548.64
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 67860 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 68262 (12 X 1 mL)

HIV9029 12 X 1 mL
EUR 1548.64
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 68262 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 68582 (16 X 1 mL)

HIV9030 16 X 1 mL
EUR 1548.64
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 68582 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 66048 (19 X 1 mL)

HIV9031 19 X 1 mL
EUR 1548.64
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 66048 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 66686 (16 X 1 mL)

HIV9033 16 X 1 mL
EUR 1548.64
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 66686 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 66632 (13 X 1 mL)

HIV9034 13 X 1 mL
EUR 1548.64
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 66632 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 62216 (4 X 1 mL)

HIV9075 4 X 1 mL
EUR 2040.56
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 62216 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 63753 (9 X 1 mL)

HIV9076 9 X 1 mL
EUR 2040.56
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 63753 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 75018 (23 X 1 mL)

HIV9077 23 X 1 mL
EUR 2040.56
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 75018 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

HIV Seroconversion Panel Donor# 79065 (5 X 1 mL)

HIV9078 5 X 1 mL
EUR 2040.56
  • What is the product classification?
  • HIV Seroconversion Panel Donor# 79065 is marked as RUO.
Description: Please contact Gentaur in order to receive the datasheet of the product.

Conclusion: For patients with stapes fixation for tympanosclerosis, the timpanoplasti stage can increase the threshold of hearing though ossicular chain reconstruction and stapes release. The major complications such as facial paralysis and sensorineural hearing loss should be avoided by delicate surgical operation.